gRPC generates cross-language stubs from Protobuf services. A Connect server can support gRPC, gRPC-Web, and the Connect protocol together, avoiding a translating proxy for browsers.
oRPC supports implementation-first and contract-first APIs, offers an RPC client, and can expose the same router through OpenAPI 3.1.1 HTTP endpoints.
tRPC lets a client reference the server router type without a separate schema or code generation. Version 11 also has an official, alpha-stage OpenAPI 3.1 generator.
notebooklm-py reverse-engineers Google's batchexecute RPC protocol, letting you programmatically control NotebookLM via Python / CLI / AI Agent — including audio, video, slides, quiz generation and more.